In 1947 something extra-terrestrial crashed into Roswell and 42 years later, hybrid descendants Max Evans (Jason Behr), Isabel Evans (Katherine Heigl) and Michael Guerin (Brendan Fehr) emerged from their incubation pods looking like six year old human children. They were eventually found roaming the desert and adopted by parents who knew nothing of their inner conflicts or supernatural gifts.
One day when classmate Liz Parker (Shiri Appleby) gets caught in crossfire at the town's Crashdown Café, Max rushes to her side and overcome by his lifelong crush on her, heals her with his hands risking exposing the group's alien identities.
The connection that took place in the café is strong and the two teenagers see into each other's souls. Liz and Max are a modern day Romeo and Juliet, drawn to each other but unable to be together, they really are world's apart!
Liz can t help but tell her best friend Maria (Majandra Delfino) and their childhood buddy - the geeky Alex Whitman (Colin Hanks). Thrust into protecting their new friends and questioning everyone's intentions, they must all survive in a town obsessed with finding and experimenting on alien lifeform.
UFO墜落現場として世界的に有名な町、ニューメキシコ州 ロズウェル。その町に住む高校生のリズ・パーカーはある日、アルバイト中に発砲事件に巻き込まれ、瀕死の重傷を負う。その時たまたま居合わせた高校の同級生、マックス・エバンズは不思議な力を発揮しリズを助ける。実は彼は1947年のUFO墜落事故の生き残りのエイリアンだった。この事件をきっかけに、リズはエイリアンが実は身近に存在することを知り、同時にマックスは極秘調査を続けるFBIや保安官に追われるようになる。エイリアンはどこから、何のために地球にきたのか？そして異星人と知りながらお互いに惹かれて行くリズとマックス。人間とエイリアンの恋愛・友情・確執などをSFとロマンスを盛り込んで描く異色青春ドラマ。
